The Biostatistics Laboratory at the University of Chicago

The Biostatistics Laboratory is a resource for advice on biostatistics, including research design and statistical analysis. We actively collaborate with investigators, and we encourage potential investigators to contact us at an early stage in their planning. The Biostatistics Clinic has been established to provide free, short-term statistical consultation. This could include:
  • discussion about study design,
  • sample size calculations*,
  • advice on organizing data for analysis,
  • basic data analysis, (requiring minimal data cleaning)
  • advice to those conducting their own analyses,
  • initial planning and referral for more extensive consultation.
* This requires substantial input from the investigator and is dependent on the study design. In order to be well prepared for the Clinic appointment, please review this article by Eng. Additionally, if the study design has not been fully determined, then time will first need to be spent discussing this.

Assistance with grant preparation will usually require more than the 1 hour clinic, so we strongly encourage initially requesting longer-term collaborative support (“Research Support Request”) instead of the Clinic, and doing so as early as possible.

Staffed by members of the Biostatistics Laboratory, the Clinic is currently held on Tuesdays from 9-1 with one-hour time slots available. Appointments are required. This service is funded in part by the University of Chicago Institute for Translational Medicine (CTSA) to lower barriers and to accelerate clinical and translational research.

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The Biostatistics Laboratory is located in the Medical Center on the 3rd floor of the Mothers Aid Research Pavilion (MARP - R-corridor). This can only be accessed from the staircase next to the Student Care Center. The nearest hospital entrance is the Goldblatt Lobby.

Pilot Study Design and Planning

Pilot studies are an important part of clinical, translational research because they can lead to refinement of procedures and hypotheses and can generate preliminary data prior to undertaking a larger study. As with all other aspects of research, good study design and planning is essential for a pilot study. The following links detail issues to consider when designing these studies: a pilot study checklist  and slides from a presentation on pilot studies.